Pre-injection Alco Swabs, Pack of 100

Product Information

A power calculation was performed, but the study did not recruit enough participants to meet this threshold and to appropriately measure to main outcome. Rather, the researchers powered it for the secondary outcome (i.e., incidence of delayed pain). Although the authors indicated that it was not feasible to recruit a sufficient number of patients for the primary outcome, this may limit the interpretation of results and conclusion of the study. Subject to the aforementioned limitations, the views expressed herein are those of CADTH and do not necessarily represent the views of Canada’s federal, provincial, or territorial governments or any third party supplier of information. Authorisation will be subject to the condition that the products are returned to VWR Customer Service Centre or to the manufacturer or other source and by the method advised by VWR.

VWR shall provide services to the customer in accordance with the specification agreed between them from time to time. Such services will be provided with all reasonable care and skill. The purpose of this report is to summarize the evidence regarding the clinical effectiveness and cost-effectiveness of skin preparation prior to injections. Evidence-based guidelines regarding preparing the skin for injection will also be sought. VWR may at any time, without limiting any other rights and remedies that it may have, set off any amount owing to it by the customer under the contract against any amount payable by VWR to the customer (whether under the contract or a separate agreement). Delivery Nothing in this contract shall limit or exclude VWR’s liability for death or personal injury caused by its negligence, fraud, fraudulent misrepresentation, or any other matter in respect of which it would be unlawful for VWR to exclude or restrict liability. Subject to this, in view of the responsibilities of the customer set out in the above paragraphs: While care has been taken to ensure that the information prepared by CADTH in this document is accurate, complete, and up-to-date as at the applicable date the material was first published by CADTH, CADTH does not make any guarantees to that effect. CADTH does not guarantee and is not responsible for the quality, currency, propriety, accuracy, or reasonableness of any statements, information, or conclusions contained in any third-party materials used in preparing this document. The views and opinions of third parties published in this document do not necessarily state or reflect those of CADTH.Any additional or special terms included by VWR in its written acceptance shall form part of the contract. The terms and conditions of the contract apply equally to the supply of both products and services except where application to one or the other is specified.

the total liability of VWR for any loss or damage suffered by a customer in connection with the supply of the products under this contract is limited to the invoice price of the products in relation to which loss or damage is claimed.All intellectual property rights arising out of or in connection with the services shall be owned by VWR. Termination CADTH is not responsible for any errors, omissions, injury, loss, or damage arising from or relating to the use (or misuse) of any information, statements, or conclusions contained in or implied by the contents of this document or any of the source materials. Price on application’ (POA) quotations and all other quotations do not constitute offers and will be valid for 30 days from the date of the quotation, unless otherwise notified by VWR.

Follow-up telephone surveys were available for 99% (168/170) on Day 1, 99% (168/170) on Day 5, and 94% (160/170) on Day 14 postvaccination

This is the first RCT to specifically examine the effect of alcohol swab skin cleansing on the incidence of local skin reactions and infection in children undergoing vaccine injections. We found no evidence of a difference in the rate of local skin reactions and no cases of cellulitis or infectious abscess when alcohol swabs were and were not used” (pp997) The customer shall cooperate with VWR in all matters relating to the services, provide all such access and information as is necessary and obtain any licences permissions and consents required before commencement of the services. Authorisation for the return of products which fail to meet current published manufacturer’s specifications must be requested in writing within 28 days of delivery. VWR will assist customers, at customers’ expense, to obtain any manufacturer’s warranty consistent with that granted to VWR. VWR shall under no circumstances whatsoever be liable to the customer (whether in contract, tort (including negligence), breach of statutory duty or otherwise), for any loss of profit, or any indirect or consequential loss arising in connection with the supply of products under this contract; and

These terms and conditions cover all sales of products and services by VWR International Ltd (VWR) in the United Kingdom and any information and advice given whether charged for or not, unless otherwise agreed by VWR in writing. These terms and conditions apply to the exclusion of any other terms submitted by the customer or which are implied by any trade, custom, practice or course of dealing. Customer Accounts The customer is required to ensure that the use of any products supplied by VWR does not infringe the intellectual property rights of any third party and the customer shall indemnify VWR against any claims made against VWR by any third party in relation to any such infringement or alleged infringement. Inclusion criteria: Healthy children aged zero to 18 years who qualified for vaccination in accordance with the Ontario Immunization Schedule were eligible. Evidence from the randomized-controlled trial suggested that alcohol swabbing does not reduce local skin reactions prior to vaccination. The study had reasonable attempts at blinding where possible and described the main outcomes, recruitment process and overall results. There were no statistically significant differences between the alcohol swab group and control group for delayed pain, redness, swelling and warmth to touch while there were no reported cases of cellulitis and infectious abscesses. Post-hoc analysis showed that the duration of pain was statistically significantly higher in the alcohol swab group compared to the control group although the clinical significance of this outcome not discussed by the authors. The study was underpowered to detect differences in the primary outcome of skin infection and instead focused on the differences of local skin reaction between groups. Therefore, the study did not answer the primary outcome and a larger sample size is needed to detect whether alcohol swabbing does reduce the risk of infection. While the authors report that this is one of the first studies to report on the effectiveness of alcohol swabbing prior to vaccinations, it is difficult to draw definitive conclusions from a single trial. 8

In view of the wide range of uses of chemicals and apparatus, the customer will be solely responsible for determining the suitability and specification of products, services, information and advice for its purposes. One randomized controlled trial was included in this report comparing skin preparation to no skin preparation prior to injection. No relevant cost-effectiveness studies or evidence-based guidelines were identified regarding preparing the skin for injection. This document is prepared and intended for use in the context of the Canadian health care system. The use of this document outside of Canada is done so at the user’s own risk.